Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 6/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | PDE6D | O43924 | 1/20 | 0.65 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.65 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.65 |
| ▸ | CFTR | P13569 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568415 | 0.87 | MAPT (1.00) | MAPTLMNATP53TSHRHSD17B10 | |
| SCHEMBL6562002 | 0.85 | GALR3 (0.74) | MAPTLMNATP53TSHRHSD17B10 | |
| SCHEMBL30934017 | 0.83 | MAPT (0.80) | MAPTLMNATP53TSHRHSD17B10 | |
| SCHEMBL29076181 | 0.83 | MAPT (0.67) | MAPTLMNATP53TSHRHSD17B10 | |
| SCHEMBL30581242 | 0.83 | MAPT (0.67) | MAPTLMNATP53TSHRHSD17B10 | |
| SCHEMBL28322548 | 0.81 | TP53 (0.71) | MAPTLMNATP53TSHRHTT | |
| SCHEMBL29412044 | 0.81 | TP53 (1.00) | MAPTLMNATP53TSHRHSD17B10 | |
| SCHEMBL29412062 | 0.80 | TP53 (0.78) | MAPTLMNATP53HTTALDH1A1 | |
| SCHEMBL229828 | 0.79 | ALDH1A1 (1.00) | MAPTLMNATP53TSHRHSD17B10 | |
| SCHEMBL20797646 | 0.79 | MYC (0.63) | MAPTLMNATP53TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250202-B | 2,3- disubstituted benzenes and imidazo [1,2-a] pyrimidines and its preparation method and application | 陕西师范大学 | 2019-10-25 | — | — | CN | disclosed |
| CN-108250202-A | 2,3- disubstituted benzenes and imidazo [1,2-a] pyrimidines and its preparation method and application | 陕西师范大学 | 2018-07-06 | — | — | CN | disclosed |