Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604019 | 0.81 | TDP1 (0.39) | TDP1NFKB1NFKB2RELADGAT1 | |
| SCHEMBL101218 | 0.80 | DGAT1 (0.46) | TDP1NFKB1NFKB2RELADGAT1 | |
| SCHEMBL22305381 | 0.79 | TDP1 (0.41) | TDP1CA1CA2CA7MEN1 | |
| SCHEMBL10227847 | 0.79 | TDP1 (0.38) | TDP1NFKB1NFKB2RELADGAT1 | |
| SCHEMBL1522412 | 0.78 | DGAT1 (0.44) | TDP1NFKB1NFKB2RELADGAT1 | |
| SCHEMBL6272856 | 0.78 | DGAT1 (0.44) | TDP1NFKB1NFKB2RELADGAT1 | |
| Potassium SCHEMBL29554503 | 0.78 | DGAT1 (0.44) | TDP1NFKB1NFKB2RELADGAT1 | |
| SCHEMBL320540 | 0.77 | MAOA (0.40) | TDP1NFKB1NFKB2RELADGAT1 | |
| Hydrochloric Acid SCHEMBL7342949 | 0.76 | MAOA (0.39) | TDP1NFKB1NFKB2RELADGAT1 | |
| SCHEMBL8233731 | 0.76 | TDP1 (0.36) | TDP1NFKB1NFKB2RELADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105434-A | The polypeptide and application thereof of stitching and suture | 哈佛大学的校长及成员们 | 2019-08-09 | — | — | CN | disclosed |
| CN-102510755-A | Bifunctional stapled polypeptides and uses thereof | HARVARD COLLEGE | 2012-06-20 | — | — | CN | disclosed |
| EP-0933993-A4 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARM INC (US) | 2004-09-08 | — | — | EP | disclosed |
| CN-1227466-A | Substituted cyclopentane compounds useful as neuraminidase inhibitors | BIOCRYST PHARM INC (US) | 1999-09-01 | — | — | CN | disclosed |
| EP-0933993-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS INC. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997047194-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-12-18 | — | — | WO | disclosed |