Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563522 | 0.96 | MAPT (0.51) | TSHRMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL6549016 | 0.91 | MAPT (0.47) | TSHRMAPTPRSS1ACRLMNA | |
| SCHEMBL6547272 | 0.87 | PDCD1 (0.44) | TSHRMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL6547911 | 0.85 | MAPT (0.42) | TSHRMAPTPRSS1ACRKMT2A | |
| SCHEMBL10799094 | 0.84 | LMNA (0.55) | TSHRMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL9488678 | 0.84 | TSHR (0.55) | TSHRMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL6393368 | 0.83 | TSHR (0.44) | TSHRMAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL6393362 | 0.83 | TSHR (0.44) | TSHRMAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL6561968 | 0.82 | PRSS1 (0.44) | TSHRMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL6561998 | 0.82 | TP53 (0.46) | TSHRMAPTSMN1; SMN2PRSS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225212-B1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6677475-B2 | FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-01-13 | — | — | US | disclosed |
| EP-1225212-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-07-24 | — | — | EP | disclosed |