Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | ACR | P10323 | 2/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549016 | 0.96 | MAPT (0.47) | MAPTALDH1A1TSHRKMT2AL3MBTL1 | |
| SCHEMBL6561998 | 0.95 | TP53 (0.46) | PDCD1CD274MAPTALDH1A1TSHR | |
| SCHEMBL6561968 | 0.95 | PRSS1 (0.44) | PDCD1CD274MAPTALDH1A1TSHR | |
| SCHEMBL6387977 | 0.92 | HSD17B10 (0.50) | PDCD1CD274MAPTTSHRKMT2A | |
| SCHEMBL6564025 | 0.92 | MAPT (0.52) | PDCD1CD274MAPTALDH1A1TSHR | |
| SCHEMBL6562110 | 0.92 | KMT2A (0.42) | PDCD1CD274MAPTALDH1A1TSHR | |
| SCHEMBL6563522 | 0.92 | MAPT (0.51) | MAPTTSHRKMT2ATHRBL3MBTL1 | |
| SCHEMBL6562379 | 0.92 | MAPT (0.52) | PDCD1CD274MAPTALDH1A1TSHR | |
| SCHEMBL6390324 | 0.91 | TSHR (0.45) | MAPTALDH1A1TSHRKMT2ATHRB | |
| SCHEMBL6388175 | 0.91 | TSHR (0.45) | MAPTALDH1A1TSHRKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730371-B2 | LIQUID CRYSTAL DISPLAY | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-05-04 | — | — | US | disclosed |
| EP-1249484-B1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-20030054119-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO., INC. | 2003-03-20 | — | — | US | disclosed |
| EP-1249484-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030054119-A1 | Optically active compound and liquid crystal composition containing the compound | HDHD5, THOC2, TDO2 | PDCD1 1767/4885CD274 2993/4885MAPT 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.