Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143940 | 0.93 | ALDH1A1 (0.45) | PGRALDH1A1LMNAPOLBPKM | |
| SCHEMBL6603184 | 0.93 | MAOB (0.47) | PGRALDH1A1LMNAPOLBPKM | |
| SCHEMBL6600265 | 0.93 | ALDH1A1 (0.46) | PGRALDH1A1LMNAPOLBPKM | |
| SCHEMBL6582371 | 0.93 | NPC1 (0.49) | PGRALDH1A1LMNAPOLBPKM | |
| SCHEMBL6581923 | 0.91 | NPC1 (0.48) | PGRALDH1A1LMNAPOLBPKM | |
| SCHEMBL6563907 | 0.90 | ALDH1A1 (0.51) | PGRALDH1A1LMNAPOLBMAOB | |
| SCHEMBL6601223 | 0.90 | ALDH1A1 (0.44) | PGRALDH1A1LMNAPOLBPKM | |
| SCHEMBL6600753 | 0.89 | SMN1; SMN2 (0.44) | PGRALDH1A1LMNAPOLBPKM | |
| SCHEMBL144055 | 0.89 | MAOB (0.48) | PGRALDH1A1LMNAPOLBPKM | |
| SCHEMBL6602816 | 0.89 | NPC1 (0.48) | PGRALDH1A1LMNAPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124809-B1 | BENZOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 2004-03-24 | — | — | EP | claimed |