Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673359 | 0.83 | AKR1C3 (0.61) | AKR1C3ALDH1A1NPSR1MAPTTDP1 | |
| SCHEMBL9712470 | 0.80 | AKR1C3 (0.53) | AKR1C3ALDH1A1MAPTHTTTDP1 | |
| SCHEMBL2784914 | 0.80 | AKR1C3 (0.61) | AKR1C3ALDH1A1NPSR1MAPTHTT | |
| SCHEMBL11522092 | 0.79 | CDC25B (0.49) | AKR1C3ALDH1A1MAPTTDP1CDC25B | |
| SCHEMBL9712528 | 0.78 | AKR1C3 (0.50) | AKR1C3ALDH1A1NPSR1MAPTHTT | |
| SCHEMBL7559439 | 0.76 | AKR1C3 (0.46) | AKR1C3ALDH1A1NPSR1MAPTTDP1 | |
| SCHEMBL2408127 | 0.75 | HNF4A (0.40) | ALDH1A1MAPTHTTTDP1SMN1; SMN2 | |
| SCHEMBL9249733 | 0.75 | AKR1C3 (0.48) | AKR1C3ALDH1A1NPSR1MAPTTDP1 | |
| SCHEMBL8523127 | 0.75 | HNF4A (0.60) | AKR1C3ALDH1A1NPSR1MAPTHTT | |
| SCHEMBL934810 | 0.74 | AKR1C3 (0.59) | AKR1C3ALDH1A1NPSR1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397347-A2 | PREPARATION OF 17-PHENYL- 18, 19, 20- TRINOR-PGF2A AND ITS DERIVATIVES | Finetech Laboratories Ltd. (IL) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002096868-A2 | PREPARATION OF 17-PHENYL- 18, 19, 20- TRINOR-PGF2A AND ITS DERIVATIVES | FINETECH LABORATORIES LTD. (IL) | 2002-12-05 | — | — | WO | disclosed |