Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249733 | 0.88 | AKR1C3 (0.48) | AKR1C3ALDH1A1LMNATDP1MAPT | |
| SCHEMBL9712350 | 0.87 | NR4A1 (0.50) | AKR1C3ALDH1A1MAPTSRD5A2SMN1; SMN2 | |
| SCHEMBL7673359 | 0.86 | AKR1C3 (0.61) | AKR1C3ALDH1A1LMNATDP1MAPT | |
| SCHEMBL10783038 | 0.84 | POLB (0.58) | ALDH1A1TDP1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9712528 | 0.84 | AKR1C3 (0.50) | AKR1C3ALDH1A1LMNATDP1MAPT | |
| SCHEMBL6562273 | 0.80 | AKR1C3 (0.54) | AKR1C3ALDH1A1LMNATDP1MAPT | |
| SCHEMBL11613229 | 0.79 | AKR1C3 (0.59) | AKR1C3ALDH1A1LMNATDP1MAPT | |
| SCHEMBL9712611 | 0.78 | ALDH1A1 (0.50) | AKR1C3ALDH1A1LMNATDP1MAPT | |
| SCHEMBL363400 | 0.76 | ALDH1A1 (0.52) | AKR1C3ALDH1A1LMNAMAPTSRD5A2 | |
| SCHEMBL11189754 | 0.76 | AKR1C3 (0.84) | AKR1C3ALDH1A1LMNATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |