SCHEMBL6562370

SCHEMBL6562370

C#C[Si](C)(C#C)OC(C)=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6562713 0.79 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL6562870 0.76 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL6562729 0.76 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL6564128 0.76 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL6562735 0.75
SCHEMBL6562949 0.72 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL9704519 0.71
SCHEMBL6562675 0.70 ALDH1A1 (0.35) ALDH1A1
SCHEMBL6562677 0.69 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL63651 0.67 ALDH1A1 (0.41) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122746-B1 Composition for film formation and insulating film JSR CORP (JP) 2004-09-22 EP disclosed
US-6468589-B2 A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING JSR CORPORATION (JP) 2002-10-22 US disclosed
US-20010012870-A1 Composition for film formation and insulating film JSR CORPORATION (JP) 2001-08-09 US disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed