SCHEMBL6562494

SCHEMBL6562494

NC(=S)NCc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
MAOB P27338 2/20 0.57
MAOA P21397 1/20 0.57
MAPT P10636 3/20 0.54
CA2 P00918 2/20 0.54
ALDH1A1 P00352 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
LOXL2 Q9Y4K0 1/20 0.52
CA1 P00915 1/20 0.51
CYP19A1 P11511 1/20 0.51
IDO1 P14902 2/20 0.50
EPHX1 P07099 1/20 0.50
CHRM2 P08172 1/20 0.50
PTPRF P10586 1/20 0.50
PTPN2 P17706 1/20 0.50
PTPN1 P18031 1/20 0.50
PTPN11 Q06124 1/20 0.50
GAA P10253 1/20 0.49
TSHR P16473 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31011681 0.86 MEN1 (0.68) MEN1KMT2AMAOBMAOAMAPT
SCHEMBL4587579 0.84 CA2 (0.58) MEN1KMT2AMAOBMAOACA2
SCHEMBL9402193 0.83 MEN1 (0.62) MEN1KMT2AMAOBMAOAMAPT
SCHEMBL9402341 0.82 MEN1 (0.50) MEN1KMT2AMAOBMAOAMAPT
SCHEMBL20496876 0.80 MEN1 (0.62) MEN1KMT2AMAOBMAOAMAPT
SCHEMBL9402337 0.79 IDO1 (0.58) MEN1KMT2AMAOBMAOAMAPT
SCHEMBL1521016 0.79 PTPRF (0.57) MEN1KMT2AMAOBMAOACA2
SCHEMBL27968659 0.79 L3MBTL1 (0.57) MEN1KMT2AMAOBMAOACA2
SCHEMBL2850347 0.78 APOBEC3A (0.58) MEN1KMT2AMAOBMAOACA2
Sulfuric Acid SCHEMBL10890614 0.78 CA2 (0.56) MEN1KMT2AMAOBMAOACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084793-A Diamine monomer containing imidazole structure, and preparation method and application thereof 波米科技有限公司 2024-05-28 CN disclosed
EP-1085009-B1 INDAN DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2004-11-10 EP disclosed
EP-0934296-B1 CHROMAN DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2003-06-04 EP disclosed
US-6486178-B1 Indane derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-26 US disclosed
EP-1085009-A1 INDAN DERIVATIVES Nissan Chemical Industries, Ltd. (JP) 2001-03-21 EP disclosed
US-6066631-A Chroman derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-05-23 US disclosed
WO-2000012492-A1 BENZOXAZINE DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-09 WO disclosed
EP-0934296-A1 CHROMAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1999-08-11 EP disclosed
WO-1998004542-A1 CHROMAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-02-05 WO disclosed