⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564971 | 0.88 | — | — | |
| SCHEMBL6566273 | 0.87 | — | — | |
| SCHEMBL6563883 | 0.87 | — | — | |
| SCHEMBL6564709 | 0.87 | — | — | |
| SCHEMBL6566351 | 0.87 | DAO (0.30) | — | |
| SCHEMBL6564820 | 0.85 | — | — | |
| SCHEMBL6564525 | 0.84 | VDR (0.41) | — | |
| SCHEMBL6563013 | 0.84 | RAB9A (0.33) | — | |
| SCHEMBL6565055 | 0.84 | — | — | |
| SCHEMBL6563890 | 0.78 | MGMT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |