Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882624 | 0.92 | SMN1; SMN2 (0.45) | NR1H4MRGPRX4SMN1; SMN2RAB9AFFAR1 | |
| SCHEMBL6564818 | 0.90 | MRGPRX4 (0.54) | NR1H4MRGPRX4FFAR1NR4A1NR4A2 | |
| SCHEMBL6566321 | 0.89 | MRGPRX4 (0.48) | NR1H4MRGPRX4SMN1; SMN2TP53PKM | |
| SCHEMBL6565076 | 0.88 | MRGPRX4 (0.47) | NR1H4MRGPRX4SMN1; SMN2RAB9AFFAR1 | |
| SCHEMBL6888088 | 0.84 | PPARG (0.46) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL6888101 | 0.83 | MRGPRX4 (0.47) | NR1H4MRGPRX4SMN1; SMN2RAB9AFFAR1 | |
| SCHEMBL9394690 | 0.83 | NR4A2 (0.64) | NR1H4MRGPRX4SMN1; SMN2TP53PKM | |
| SCHEMBL6562731 | 0.82 | MRGPRX4 (0.48) | MRGPRX4SMN1; SMN2TP53NFKB1NFKB2 | |
| SCHEMBL6562842 | 0.82 | MRGPRX4 (0.47) | NR1H4MRGPRX4SMN1; SMN2TP53PKM | |
| SCHEMBL6886884 | 0.82 | MRGPRX4 (0.43) | MRGPRX4SMN1; SMN2PKMRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |