Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566321 | 0.92 | MRGPRX4 (0.48) | MRGPRX4RAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6882624 | 0.90 | SMN1; SMN2 (0.45) | MRGPRX4MAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6885435 | 0.90 | MRGPRX4 (0.41) | MRGPRX4MAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6888101 | 0.88 | MRGPRX4 (0.47) | MRGPRX4MAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6886989 | 0.84 | MAPT (0.53) | MRGPRX4MAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6565076 | 0.83 | MRGPRX4 (0.47) | MRGPRX4RAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL6562842 | 0.83 | MRGPRX4 (0.47) | MRGPRX4RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6888088 | 0.83 | PPARG (0.46) | MRGPRX4MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6562778 | 0.82 | NR1H4 (0.48) | MRGPRX4RAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL2851878 | 0.81 | RAB9A (0.44) | MRGPRX4MAPTRAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |