Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885435 | 0.92 | MRGPRX4 (0.41) | MRGPRX4PPARASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL6566321 | 0.89 | MRGPRX4 (0.48) | MRGPRX4PPARANR4A2TP53PKM | |
| SCHEMBL6565076 | 0.88 | MRGPRX4 (0.47) | MRGPRX4PPARANR4A2SMN1; SMN2RAB9A | |
| SCHEMBL6563998 | 0.86 | MRGPRX4 (0.53) | MRGPRX4NR4A2MAOBFFAR1 | |
| SCHEMBL6888088 | 0.84 | PPARG (0.46) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6886884 | 0.83 | MRGPRX4 (0.43) | MRGPRX4PKMSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL6566454 | 0.83 | MRGPRX4 (0.47) | MRGPRX4TP53NFKB1NFKB2RELA | |
| SCHEMBL6562778 | 0.82 | NR1H4 (0.48) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL6564818 | 0.80 | MRGPRX4 (0.54) | MRGPRX4NR4A2NR1H4FFAR1 | |
| SCHEMBL6890556 | 0.78 | NR1H2 (0.47) | MRGPRX4NR4A2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |