Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | THPO | P40225 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564378 | 0.92 | APP (0.39) | APPNPC1GRM5RAB9ASMN1; SMN2 | |
| SCHEMBL3947886 | 0.90 | NQO1 (0.33) | — | |
| SCHEMBL3946394 | 0.86 | GRM5 (0.35) | GRM5 | |
| SCHEMBL6562877 | 0.86 | APP (0.44) | APPNPC1GRM5RAB9ASMN1; SMN2 | |
| SCHEMBL14299206 | 0.85 | RELA (0.51) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL6564478 | 0.85 | APP (0.39) | APPNPC1GRM5RAB9ASMN1; SMN2 | |
| SCHEMBL6561451 | 0.84 | APP (0.42) | APPNPC1GRM5RAB9ASMN1; SMN2 | |
| SCHEMBL6564363 | 0.84 | APP (0.42) | APPNPC1GRM5RAB9ASMN1; SMN2 | |
| SCHEMBL6561443 | 0.82 | APP (0.41) | APPNPC1GRM5RAB9ASMN1; SMN2 | |
| SCHEMBL21853737 | 0.82 | GRM5 (0.41) | NPC1GRM5SMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081921-B | Silicon-based hard mask | 罗门哈斯电子材料有限责任公司 | 2021-07-06 | — | — | CN | disclosed |
| US-11033889-B2 | Palladium acyclic diaminocarbene complexes as precatalysts for Hiyama coupling and the tandem one-pot fluoride free Hiyama coupling/cyclization for the synthesis of biologically relevant | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2021-06-15 | — | — | US | disclosed |
| US-11033889-B2 | Palladium acyclic diaminocarbene complexes as precatalysts for Hiyama coupling and the tandem one-pot fluoride free Hiyama coupling/cyclization for the synthesis of biologically relevant | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2021-06-15 | — | — | US | disclosed |
| US-10818493-B2 | Silicon-based hardmask | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2020-10-27 | — | — | US | disclosed |
| US-20200122132-A1 | PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2020-04-23 | — | — | US | disclosed |
| US-20200122132-A1 | PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2020-04-23 | — | — | US | disclosed |
| US-20190115209-A1 | SILICON-BASED HARDMASK | ROHM & HAAS ELECT MAT (US) | 2019-04-18 | — | — | US | disclosed |
| US-10186424-B2 | Silicon-based hardmask | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2019-01-22 | — | — | US | disclosed |
| US-20180366319-A1 | SILICON-BASED HARDMASK | ROHM & HAAS ELECT MAT (US) | 2018-12-20 | — | — | US | disclosed |
| EP-1122746-B1 | Composition for film formation and insulating film | JSR CORP (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6468589-B2 | A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING | JSR CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| US-20010012870-A1 | Composition for film formation and insulating film | JSR CORPORATION (JP) | 2001-08-09 | — | — | US | disclosed |
| EP-1122746-A1 | Composition for film formation and insulating film | JSR Corporation (JP) | 2001-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200122132-A1 | PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT | PAICS, AOC1, FLI1 | APP 3665/4885NPC1 3687/4885GRM5 2293/4885 |
| US-11033889-B2 | Palladium acyclic diaminocarbene complexes as precatalysts for Hiyama coupling and the tandem one-pot fluoride free Hiyama coupling/cyclization for the synthesis of biologically relevant | PAICS, AOC1, FLI1 | APP 3665/4885NPC1 3687/4885GRM5 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.