Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 9/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6563971 | 0.99 | CXCR2 (0.55) | CXCR2CXCR1KMT2ACA12CA1 | |
| SCHEMBL5445412 | 0.95 | CXCR2 (0.58) | CXCR2CXCR1KMT2A | |
| SCHEMBL6564696 | 0.92 | CXCR2 (0.49) | CXCR2KMT2ACA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL6563370 | 0.91 | CXCR2 (0.48) | CXCR2KMT2ACA12CA1CA2 | |
| SCHEMBL6564950 | 0.89 | CXCR2 (0.59) | CXCR2KMT2A | |
| Hydrochloric Acid SCHEMBL6564140 | 0.88 | CXCR2 (0.58) | CXCR2KMT2AKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL4586843 | 0.85 | LMNA (0.51) | CXCR2CXCR1KMT2APOLB | |
| SCHEMBL6564640 | 0.83 | CXCR2 (0.61) | CXCR2 | |
| Hydrochloric Acid SCHEMBL7554449 | 0.82 | KDM4E (0.54) | CXCR2KMT2AKDM4EPOLB | |
| SCHEMBL6564942 | 0.82 | CXCR2 (0.69) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161232-B1 | HYDROXY DIPHENYL UREA SULFONAMIDES AS IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-03-24 | — | — | EP | claimed |