Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.61 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4593660 | 0.99 | CXCR2 (0.60) | CXCR2CX3CR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6564950 | 0.95 | CXCR2 (0.59) | CXCR2CX3CR1 | |
| Hydrochloric Acid SCHEMBL6564140 | 0.94 | CXCR2 (0.58) | CXCR2CX3CR1 | |
| Hydrochloric Acid SCHEMBL4586843 | 0.92 | LMNA (0.51) | CXCR2CX3CR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5445412 | 0.88 | CXCR2 (0.58) | CXCR2CX3CR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6564696 | 0.87 | CXCR2 (0.49) | CXCR2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6563370 | 0.86 | CXCR2 (0.48) | CXCR2SMN1; SMN2 | |
| SCHEMBL6562852 | 0.83 | CXCR2 (0.56) | CXCR2 | |
| SCHEMBL4593448 | 0.82 | CXCR2 (0.77) | CXCR2CX3CR1 | |
| Hydrochloric Acid SCHEMBL6563971 | 0.82 | CXCR2 (0.55) | CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161232-B1 | HYDROXY DIPHENYL UREA SULFONAMIDES AS IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-03-24 | — | — | EP | claimed |