Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560550 | 0.90 | PHGDH (0.47) | PHGDHALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6560837 | 0.88 | KMT2A (0.46) | ALDH1A1CYP2C19KMT2AMEN1DRD4 | |
| SCHEMBL6559635 | 0.86 | ALDH1A1 (0.61) | PHGDHALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6561321 | 0.84 | KMT2A (0.52) | PHGDHALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6562908 | 0.81 | PHGDH (0.45) | PHGDHALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7804720 | 0.80 | KMT2A (0.41) | ALDH1A1CYP2C19KMT2AMEN1MAPT | |
| SCHEMBL6562602 | 0.80 | PHGDH (0.57) | PHGDHALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6562659 | 0.79 | PHGDH (0.54) | PHGDHALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6560454 | 0.78 | PHGDH (0.46) | PHGDHALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7803116 | 0.78 | KMT2A (0.46) | PHGDHALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075469-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |
| US-6683184-B2 | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2004-01-27 | — | — | US | disclosed |
| US-20030092910-A1 | Piperazine derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092910-A1 | Piperazine derivatives and process for the preparation thereof | CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS | PHGDH 2923/4885ALDH1A1 58/4885CYP1A2 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.