Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560562 | 0.89 | LMNA (0.42) | PHGDHLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6560843 | 0.88 | MAPT (0.42) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6559635 | 0.84 | ALDH1A1 (0.61) | PHGDHALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6561321 | 0.82 | KMT2A (0.52) | PHGDHLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6562891 | 0.81 | PHGDH (0.45) | PHGDHALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6562659 | 0.81 | PHGDH (0.54) | PHGDHALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL7804724 | 0.80 | PDGFRB (0.39) | LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6562602 | 0.80 | PHGDH (0.57) | PHGDHLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6560454 | 0.78 | PHGDH (0.46) | PHGDHALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6562764 | 0.77 | MAPT (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075469-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |
| US-6683184-B2 | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2004-01-27 | — | — | US | disclosed |