SCHEMBL6562897

SCHEMBL6562897

CO[Si](C#Cc1ccccc1)(OC)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.48
GRM5 P41594 7/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
THPO P40225 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
CYP2D6 P10635 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
KMT2A Q03164 1/20 0.42
GRIN2B Q13224 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6564413 0.91 APP (0.44) APPGRM5NPC1RAB9ASMN1; SMN2
SCHEMBL1639959 0.88 APP (0.37) APPGRM5CYP1A2KCNH2
SCHEMBL3953430 0.84 GRM5 (0.41) GRM5
SCHEMBL6563101 0.82 APP (0.48) APPGRM5NPC1RAB9ASMN1; SMN2
SCHEMBL6562555 0.82 APP (0.48) APPGRM5NPC1RAB9ASMN1; SMN2
SCHEMBL6564353 0.80 APP (0.46) APPGRM5NPC1RAB9ASMN1; SMN2
SCHEMBL6564060 0.80 APP (0.46) APPGRM5NPC1RAB9ASMN1; SMN2
SCHEMBL1639958 0.79 GRM5 (0.32) GRM5CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL6562820 0.77 APP (0.42) APPGRM5NPC1RAB9ASMN1; SMN2
SCHEMBL6562837 0.77 APP (0.42) APPGRM5NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122013440-A Polymer PI fiber heat preservation cotton and preparation method thereof 嘉兴自然三禾新材料科技有限公司 2026-05-12 CN disclosed
CN-119257122-A Nanometer pesticide stimulated Raman tracing probe and preparation method and application thereof 安徽农业大学 2025-01-07 CN disclosed
US-10818493-B2 Silicon-based hardmask ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-10-27 US disclosed
US-20190115209-A1 SILICON-BASED HARDMASK ROHM & HAAS ELECT MAT (US) 2019-04-18 US disclosed
US-10186424-B2 Silicon-based hardmask ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2019-01-22 US disclosed
US-20180366319-A1 SILICON-BASED HARDMASK ROHM & HAAS ELECT MAT (US) 2018-12-20 US disclosed
US-9657039-B2 Production method for alkoxysilanes NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-05-23 US disclosed
US-20160002271-A1 PRODUCTION METHOD FOR ALKOXYSILANES NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2016-01-07 US disclosed
CN-101970572-B Photocurable composition SEKISUI CHEMICAL CO LTD 2014-01-29 CN disclosed
EP-1122746-B1 Composition for film formation and insulating film JSR CORP (JP) 2004-09-22 EP disclosed
CN-1524104-A Photoreactive composition ��Ԩ��ѧ��ҵ��ʽ���� 2004-08-25 CN disclosed
EP-1276807-A1 CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS Dow Corning Corporation (US) 2003-01-22 EP disclosed
US-6468589-B2 A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING JSR CORPORATION (JP) 2002-10-22 US disclosed
WO-2001083608-A1 CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS DOW CORNING CORPORATION (US) 2001-11-08 WO disclosed
US-20010012870-A1 Composition for film formation and insulating film JSR CORPORATION (JP) 2001-08-09 US disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002271-A1 PRODUCTION METHOD FOR ALKOXYSILANES MSMO1, MGAM, MACO1 APP 2684/4885GRM5 3796/4885NPC1 2417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.