Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 4/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562945 | 1.00 | PTPN1 (0.36) | PTPN1PTPN2PTPN6HNF4APIM1 | |
| SCHEMBL6882523 | 0.86 | PTGS2 (0.39) | PTPN1PIM1PTGS2KDM4EMAPT | |
| SCHEMBL6882521 | 0.86 | PTGS2 (0.39) | PTPN1PIM1PTGS2KDM4EMAPT | |
| SCHEMBL6562868 | 0.83 | PTPN1 (0.36) | PTPN1PTPN2PTPN6HNF4APIM1 | |
| SCHEMBL6562861 | 0.83 | PTPN1 (0.36) | PTPN1PTPN2PTPN6HNF4APIM1 | |
| SCHEMBL3283931 | 0.78 | PTPN1 (0.41) | PTPN1PTPN2PTPN6HNF4APTGS2 | |
| SCHEMBL3283927 | 0.78 | PTPN1 (0.41) | PTPN1PTPN2PTPN6HNF4APTGS2 | |
| SCHEMBL6564038 | 0.76 | LCK (0.36) | PIM1KDM4ELCK | |
| SCHEMBL27555319 | 0.74 | CDC25A (0.33) | HNF4AKDM4EMAPTGAA | |
| SCHEMBL6563032 | 0.73 | ALDH1A1 (0.37) | KDM4EKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |