Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 19/20 | 0.60 |
| ▸ | METAP1 | P53582 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932813 | 0.89 | METAP2 (0.58) | METAP2METAP1ALDH1A1CASP3SENP7 | |
| SCHEMBL6487629 | 0.89 | METAP2 (0.58) | METAP2METAP1ALDH1A1CASP3SENP7 | |
| SCHEMBL6561675 | 0.79 | METAP2 (0.59) | METAP2METAP1 | |
| SCHEMBL6485528 | 0.78 | METAP2 (0.78) | METAP2METAP1 | |
| SCHEMBL6487742 | 0.76 | METAP2 (0.72) | METAP2METAP1 | |
| SCHEMBL6477759 | 0.76 | METAP2 (0.72) | METAP2METAP1 | |
| SCHEMBL6477713 | 0.76 | METAP2 (0.72) | METAP2METAP1 | |
| SCHEMBL6476546 | 0.76 | METAP2 (0.71) | METAP2METAP1 | |
| SCHEMBL6488946 | 0.75 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL6478669 | 0.75 | METAP2 (0.61) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-B1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2004-10-27 | — | — | EP | claimed |