Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 13/20 | 0.58 |
| ▸ | METAP1 | P53582 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487629 | 1.00 | METAP2 (0.58) | METAP2METAP1ALDH1A1CASP3SENP7 | |
| SCHEMBL6563107 | 0.89 | METAP2 (0.60) | METAP2METAP1ALDH1A1CASP3SENP7 | |
| SCHEMBL6477744 | 0.78 | METAP2 (0.77) | METAP2METAP1 | |
| SCHEMBL6477713 | 0.76 | METAP2 (0.72) | METAP2METAP1 | |
| SCHEMBL6476546 | 0.75 | METAP2 (0.71) | METAP2METAP1KMT2A | |
| SCHEMBL6484734 | 0.74 | METAP2 (0.65) | METAP2METAP1 | |
| SCHEMBL6487742 | 0.74 | METAP2 (0.72) | METAP2METAP1 | |
| SCHEMBL6477759 | 0.74 | METAP2 (0.72) | METAP2METAP1KMT2AGAA | |
| SCHEMBL6484048 | 0.74 | METAP2 (1.00) | METAP2METAP1 | |
| SCHEMBL6485528 | 0.73 | METAP2 (0.78) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |