Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.36 |
| ▸ | RARB | P10826 | 8/20 | 0.36 |
| ▸ | RARG | P13631 | 8/20 | 0.36 |
| ▸ | RARA | P10276 | 5/20 | 0.36 |
| ▸ | RXRB | P28702 | 9/20 | 0.36 |
| ▸ | RXRG | P48443 | 9/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032727 | 0.81 | RXRA (0.36) | RXRARARBRARGRARARXRB | |
| SCHEMBL6032609 | 0.80 | RXRA (0.38) | RXRARARBRARGRARARXRB | |
| SCHEMBL6033044 | 0.79 | RXRA (0.59) | RXRARARBRARGRARARXRB | |
| SCHEMBL6032730 | 0.78 | RXRA (0.47) | RXRARARBRARGRARARXRB | |
| SCHEMBL6033003 | 0.78 | RXRA (0.41) | RXRARARBRARGRARARXRB | |
| SCHEMBL6032725 | 0.78 | RXRA (0.36) | RXRARARBRARGRARARXRB | |
| SCHEMBL6033264 | 0.75 | RARA (0.48) | RXRARARBRARGRARARXRB | |
| SCHEMBL6033243 | 0.74 | RXRA (0.46) | RXRARARBRARGRARARXRB | |
| SCHEMBL6033034 | 0.72 | SMN1; SMN2 (0.47) | RXRARARBRARGRARARXRB | |
| SCHEMBL6032589 | 0.72 | RARA (0.49) | RXRARARBRARGRARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086080-B1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2004-08-25 | — | — | EP | disclosed |
| EP-1086080-A1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065872-A1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 1999-12-23 | — | — | WO | disclosed |