Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.56 |
| ▸ | AR | P10275 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563196 | 1.00 | PGR (0.56) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL6567035 | 1.00 | PGR (0.56) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL6563204 | 1.00 | PGR (0.56) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL6563713 | 0.91 | NR3C1 (0.65) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL6563715 | 0.91 | NR3C1 (0.65) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL6566622 | 0.91 | NR3C1 (0.65) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL6566615 | 0.91 | NR3C1 (0.65) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL10905040 | 0.89 | AR (0.47) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL10905046 | 0.89 | AR (0.47) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL11032906 | 0.88 | AR (0.46) | PGRNR3C1ARCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399463-A1 | PROCESS TO PREPARE 11$g(b),17$g(a),21-TRIHYDROXY-6$g(a)-METHYLPREGNA-1,4-DIENE-3,20-DIONE 21-ACETATE | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002102826-A1 | PROCESS TO PREPARE 11β,17α,21-TRIHYDROXY-6α-METHYLPREGNA-1,4-DIENE-3,20-DIONE 21-ACETATE | PHARMACIA & UPJOHN COMPANY (US) | 2002-12-27 | — | — | WO | disclosed |