Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563249 | 1.00 | TSHR (0.45) | TSHRLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6561880 | 0.85 | PLK1 (0.48) | TSHRLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6560724 | 0.85 | PLK1 (0.48) | TSHRLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6560727 | 0.85 | PLK1 (0.48) | TSHRLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6560689 | 0.80 | MEN1 (0.42) | TSHRLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6560683 | 0.80 | MEN1 (0.42) | TSHRLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6560678 | 0.80 | MEN1 (0.42) | TSHRLMNAKMT2AMEN1NPC1 | |
| SCHEMBL9397130 | 0.78 | POLB (0.54) | TSHRLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6561899 | 0.75 | ALDH1A1 (0.60) | LMNAKMT2AMEN1NPC1KDM4E | |
| SCHEMBL6561870 | 0.75 | ALDH1A1 (0.60) | LMNAKMT2AMEN1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944581-A4 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0944581-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998022429-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |