Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561899 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAALMNANPC1 | |
| SCHEMBL8937488 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAALMNANPC1 | |
| SCHEMBL8937486 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAALMNANPC1 | |
| SCHEMBL8937491 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAALMNANPC1 | |
| SCHEMBL15199301 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAALMNANPC1 | |
| SCHEMBL6563346 | 0.82 | MAOB (0.45) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL6561872 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAALMNANPC1 | |
| SCHEMBL11296725 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAALMNANPC1 | |
| SCHEMBL11296722 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAALMNANPC1 | |
| SCHEMBL11891940 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944581-A4 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0944581-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998022429-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |