Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099713 | 1.00 | TSHR (0.35) | TSHRADORA2BADORA2ASLC6A3OPRM1 | |
| SCHEMBL6560374 | 0.76 | SLC6A3 (0.39) | TSHRADORA2BADORA2ASLC6A3CACNA1B | |
| SCHEMBL6949780 | 0.66 | KDM4C (0.39) | TSHRPOLBMAPTMEN1KMT2A | |
| SCHEMBL31569024 | 0.65 | LMNA (0.34) | TSHROPRM1OPRD1OGFRL1OPRK1 | |
| SCHEMBL10519881 | 0.64 | KDM4C (0.36) | TSHRSLC6A3POLBMAPTMEN1 | |
| SCHEMBL6299639 | 0.64 | KDM4C (0.44) | TSHRPOLBMAPTMEN1KMT2A | |
| SCHEMBL30903935 | 0.64 | HDAC6 (0.39) | ADORA2BADORA2AGPR119AAK1 | |
| SCHEMBL16256079 | 0.64 | METAP1 (0.38) | TSHRADORA2BADORA2ASLC6A3POLB | |
| SCHEMBL10516410 | 0.63 | KDM4C (0.34) | TSHRPOLBMAPTMEN1ALDH1A1 | |
| SCHEMBL6300033 | 0.63 | MAPT (0.49) | TSHRPOLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144365-B1 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2004-03-17 | — | — | EP | disclosed |