SCHEMBL6563401

SCHEMBL6563401

CCCCCc1ccc2cc(CCCCC)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 1/20 0.55
ESR1 P03372 2/20 0.54
ADRA2A P08913 2/20 0.54
ADORA3 P0DMS8 2/20 0.54
TACR2 P21452 2/20 0.54
SLC6A2 P23975 2/20 0.54
SLC6A4 P31645 2/20 0.54
SLC6A3 Q01959 2/20 0.54
CYP3A4 P08684 2/20 0.54
PTGS2 P35354 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
SHBG P04278 1/20 0.54
TP53 P04637 1/20 0.54
HSPD1 P10809 1/20 0.54
ADRB3 P13945 1/20 0.54
HTR2C P28335 1/20 0.54
HSPE1 P61604 1/20 0.54
HIF1A Q16665 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27995689 0.98 PTGS2 (0.57) BDKRB2ESR1ADRA2AADORA3TACR2
SCHEMBL27844768 0.98 PTGS2 (0.57) BDKRB2ESR1ADRA2AADORA3TACR2
SCHEMBL11690859 0.98 PTGS2 (0.57) BDKRB2ESR1ADRA2AADORA3TACR2
SCHEMBL11222681 0.98 PTGS2 (0.57) BDKRB2ESR1ADRA2AADORA3TACR2
SCHEMBL23635457 0.96 ESR1 (0.55) BDKRB2ESR1ADRA2AADORA3TACR2
SCHEMBL28593982 0.96 BDKRB2 (0.52) BDKRB2ESR1ADRA2AADORA3TACR2
SCHEMBL28578673 0.96 BDKRB2 (0.52) BDKRB2ESR1ADRA2AADORA3TACR2
SCHEMBL10822160 0.96 ESR1 (0.55) BDKRB2ESR1ADRA2AADORA3TACR2
SCHEMBL3724287 0.94 PTGS2 (0.53) BDKRB2ESR1ADRA2AADORA3TACR2
SCHEMBL3721391 0.94 PTGS2 (0.53) BDKRB2ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889016-B1 Process for preparing dialkylnaphthalene KOBE SEIKO SHOALSO KNOWN AS KO (JP) 2004-03-31 EP claimed
EP-0889016-A1 Process for preparing dialkylnaphthalene KABUSHIKI KAISHA KOBE SEIKO SHO also known as Kobe Steel Ltd. (JP) 1999-01-07 EP claimed
US-4612362-A Thermotropic polyester-carbonates containing 2,2-dimethyl-1,3-propanediol ALLIED CORPORATION (US) 1986-09-16 US claimed
EP-0999199-B1 Method of producing naphthalenedicarboxylic acid MITSUBISHI GAS CHEMICAL CO (JP) 2004-03-31 EP disclosed
US-6268528-B1 OXIDIZING DIALKYLNAPHTHALENE TO NAPHTHALENEDICARBOXYLIC ACID IN SOLVENT CONTAINING LOWER ALIPHATIC CARBOXYLIC ACID USING MOLECULAR OXYGEN-CONTAINING GAS IN PRESENCE OF A CATALYST COMPRISING COBALT COMPOUND, MANGANESE COMPOUND AND BROMINE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-07-31 US disclosed
EP-0999199-A1 Method of producing naphthalenedicarboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-05-10 EP disclosed
US-4612362-A Thermotropic polyester-carbonates containing 2,2-dimethyl-1,3-propanediol ALLIED CORPORATION (US) 1986-09-16 US disclosed