Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565492 | 0.87 | CNR2 (0.39) | ACACBPTPN11MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6563526 | 0.87 | PTPN11 (0.38) | ACACBPTPN11 | |
| SCHEMBL6561879 | 0.85 | PTPN11 (0.38) | ACACBPTPN11MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6564290 | 0.84 | ACACB (0.39) | ACACBF2CNR2F10HPGD | |
| SCHEMBL6563495 | 0.83 | PTPN11 (0.36) | ACACBPTPN11 | |
| SCHEMBL6563430 | 0.82 | PTPN11 (0.33) | PTPN11 | |
| SCHEMBL6565533 | 0.82 | ACACB (0.45) | ACACBPTPN11MEN1KMT2ACNR2 | |
| SCHEMBL6565417 | 0.82 | PTPN11 (0.36) | ACACBPTPN11HPGDNPC1 | |
| SCHEMBL6563395 | 0.80 | PTPN11 (0.35) | PTPN11 | |
| SCHEMBL6565215 | 0.79 | PIK3CA (0.38) | ACACBPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |