Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563137 | 0.84 | KLK5 (0.37) | — | |
| SCHEMBL6565533 | 0.81 | ACACB (0.45) | PTPN11DDB1CRBN | |
| SCHEMBL6563457 | 0.80 | ACACB (0.37) | PTPN11 | |
| SCHEMBL6565417 | 0.79 | PTPN11 (0.36) | PTPN11DDB1CRBN | |
| SCHEMBL6563526 | 0.79 | PTPN11 (0.38) | PTPN11DDB1CRBN | |
| SCHEMBL6561879 | 0.79 | PTPN11 (0.38) | PTPN11DDB1CRBN | |
| SCHEMBL6563299 | 0.79 | NAMPT (0.40) | — | |
| SCHEMBL6561973 | 0.79 | JAK1 (0.38) | PTPN11 | |
| SCHEMBL6565111 | 0.79 | — | — | |
| SCHEMBL6565215 | 0.77 | PIK3CA (0.38) | PTPN11DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |