Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563526 | 0.87 | PTPN11 (0.38) | PTPN11ACACBPTGES | |
| SCHEMBL6561879 | 0.85 | PTPN11 (0.38) | PTPN11ACACBPTGES | |
| SCHEMBL6561813 | 0.84 | PTPN11 (0.42) | PTPN11CCNCCDK8ACACBMTOR | |
| SCHEMBL6565505 | 0.83 | MTOR (0.36) | EGLN1MTORPIK3CA | |
| SCHEMBL6563457 | 0.83 | ACACB (0.37) | PTPN11ACACB | |
| SCHEMBL6565414 | 0.80 | PTPN11 (0.33) | PTPN11ACACBPTGES | |
| SCHEMBL6563283 | 0.80 | PTPN11 (0.46) | PTPN11ACACBEGLN1PTGES | |
| SCHEMBL6565533 | 0.79 | ACACB (0.45) | PTPN11ACACB | |
| SCHEMBL6565278 | 0.78 | PTPN11 (0.33) | PTPN11 | |
| SCHEMBL6561973 | 0.77 | JAK1 (0.38) | PTPN11ACACBMTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |