Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547348 | 0.92 | PDCD1 (0.57) | PDCD1CD274MAPTEGFRRXRA | |
| SCHEMBL6563509 | 0.91 | PDCD1 (0.48) | PDCD1CD274MAPTSCN1ASCN2A | |
| SCHEMBL6563502 | 0.91 | PDCD1 (0.48) | PDCD1CD274MAPTSCN1ASCN2A | |
| SCHEMBL6547284 | 0.91 | MAPT (0.44) | PDCD1CD274MAPTHCRTR1HCRTR2 | |
| SCHEMBL6547277 | 0.90 | MAPT (0.42) | PDCD1CD274MAPTHCRTR1HCRTR2 | |
| SCHEMBL6546722 | 0.86 | PDCD1 (0.40) | PDCD1CD274MAPTSCN1ASCN2A | |
| SCHEMBL6547138 | 0.85 | PDCD1 (0.50) | PDCD1CD274MAPTEGFRRXRA | |
| SCHEMBL7517699 | 0.85 | PDCD1 (0.46) | PDCD1CD274MAPTSCN1ASCN2A | |
| SCHEMBL6564029 | 0.85 | NPC1 (0.41) | MAPTHCRTR1HCRTR2SRD5A2RXRA | |
| SCHEMBL6393405 | 0.83 | ALDH1A1 (0.54) | PDCD1CD274MAPTRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225212-B1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6677475-B2 | FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20020146517-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. | 2002-10-10 | — | — | US | disclosed |
| EP-1225212-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-07-24 | — | — | EP | disclosed |