Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 8/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547284 | 0.89 | MAPT (0.44) | RARBFOLH1CYP4F2CYP4A11MAPT | |
| SCHEMBL6562354 | 0.88 | RARB (0.41) | NPC1TP53RAB9ASMN1; SMN2RARB | |
| SCHEMBL6547277 | 0.87 | MAPT (0.42) | RARBFOLH1CYP4F2CYP4A11MAPT | |
| SCHEMBL7526394 | 0.85 | PDCD1 (0.38) | NPC1SMN1; SMN2RARBCYP4F2CYP4A11 | |
| SCHEMBL6563516 | 0.85 | PDCD1 (0.48) | RARBMAPTRXRARXRBHCRTR1 | |
| SCHEMBL6562073 | 0.85 | CYP4F2 (0.48) | SMN1; SMN2RARBCYP4F2CYP4A11MAPT | |
| SCHEMBL6563509 | 0.84 | PDCD1 (0.48) | MAPTALDH1A1MEN1KMT2ARXRA | |
| SCHEMBL6563502 | 0.84 | PDCD1 (0.48) | MAPTALDH1A1MEN1KMT2ARXRA | |
| SCHEMBL6390329 | 0.83 | ALDH1A1 (0.46) | RARBMAPTALDH1A1MEN1RARA | |
| SCHEMBL6388182 | 0.83 | ALDH1A1 (0.46) | RARBMAPTALDH1A1MEN1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225212-B1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6677475-B2 | FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-01-13 | — | — | US | disclosed |
| EP-1225212-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-07-24 | — | — | EP | disclosed |