Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565512 | 0.80 | GAA (0.40) | F2PRSS1ALDH1A1GAAHSD11B1 | |
| SCHEMBL6563410 | 0.77 | GAA (0.40) | F2PRSS1ALDH1A1GAAHSD11B1 | |
| SCHEMBL6765245 | 0.77 | GAA (0.42) | F2PRSS1ALDH1A1GAAHSD11B1 | |
| SCHEMBL5885652 | 0.77 | PRSS1 (0.45) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7674335 | 0.76 | PRSS1 (0.49) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5885656 | 0.76 | PRSS1 (0.45) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL6565356 | 0.74 | GAA (0.42) | F2PRSS1ALDH1A1GAAHSD11B1 | |
| SCHEMBL6563261 | 0.73 | HSD11B1 (0.38) | F2PRSS1ALDH1A1GAAHSD11B1 | |
| SCHEMBL5099780 | 0.73 | F10 (0.42) | F2PRSS1ST14ALDH1A1GAA | |
| SCHEMBL6564299 | 0.73 | GAA (0.36) | F2PRSS1ALDH1A1GAAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |