Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561824 | 0.89 | MAPT (0.31) | MAPTSMN1; SMN2PTPN11 | |
| SCHEMBL6563459 | 0.87 | POLB (0.30) | MAPTSMN1; SMN2 | |
| SCHEMBL6561891 | 0.87 | ITGB3 (0.37) | MAPTSMN1; SMN2 | |
| SCHEMBL6562056 | 0.86 | MAPT (0.30) | MAPTSMN1; SMN2 | |
| SCHEMBL6565188 | 0.85 | PTPN11 (0.35) | MAPTSMN1; SMN2PTPN11 | |
| SCHEMBL7676164 | 0.82 | PTPN11 (0.30) | PTPN11 | |
| SCHEMBL6565327 | 0.81 | — | — | |
| SCHEMBL6563641 | 0.81 | — | — | |
| SCHEMBL6561908 | 0.80 | PTPN11 (0.33) | PTPN11 | |
| SCHEMBL6565320 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |