Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 19/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183458 | 0.72 | PDE3A (0.45) | PDE3APDE4BPDE3B | |
| SCHEMBL19831167 | 0.66 | BCHE (0.45) | BCHECES1 | |
| SCHEMBL14866666 | 0.66 | BCHE (0.45) | BCHECES1 | |
| SCHEMBL6683658 | 0.65 | PDE3A (0.40) | PDE3APDE4BPDE3B | |
| SCHEMBL2839635 | 0.65 | PDE3A (0.39) | PDE3APDE4BPDE3B | |
| SCHEMBL2844398 | 0.64 | PDE3A (0.45) | PDE3APDE4BPDE3B | |
| SCHEMBL2841986 | 0.63 | PDE3A (0.50) | PDE3APDE4BPDE3B | |
| SCHEMBL6680037 | 0.63 | PDE3A (0.39) | PDE3APDE4BPDE3B | |
| SCHEMBL7380645 | 0.62 | PDE3A (0.54) | PDE3APDE4BPDE3B | |
| SCHEMBL545862 | 0.62 | BCHE (0.47) | BCHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |