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Sugi Predict / Compounds / SCHEMBL6563664

SCHEMBL6563664

SCHEMBL6563664

CC=C(C(=O)O)c1ccccc1Oc1cc(Cl)ncn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ NPSR1 Q6W5P4 3/20 0.36
▸ HTT P42858 3/20 0.35
▸ MAPT P10636 3/20 0.35
▸ LMNA P02545 2/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ RORC P51449 1/20 0.35
▸ RORB Q92753 1/20 0.35
▸ HSP90AA1 P07900 1/20 0.35
▸ XBP1 P17861 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ KMO O15229 1/20 0.35
▸ CYP1A2 P05177 2/20 0.35
▸ CYP2C9 P11712 2/20 0.35
▸ CYP2C19 P33261 2/20 0.35
▸ ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5132454 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL713693 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL29391212 0.89 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL713694 0.89 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL713692 0.89 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL4740524 0.89 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL12503892 0.88 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL15298018 0.88 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL2854208 0.87 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL2857206 0.86 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2537832-B1 METHOD FOR PREPARING (E)-METHYL 2-[2-(6-CHLOROPYRIMIDIN-4-YLOXY)PHENYL]-3-METHOXYACRYLATE CHONGQING UNISPLENDOUR CHEM CO (CN) 2015-08-12 — — EP claimed
EP-1399427-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF Syngenta Limited (GB) 2004-03-24 — — EP claimed
WO-2002100837-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LIMITED (GB) 2002-12-19 — — WO claimed
EP-2537832-B1 METHOD FOR PREPARING (E)-METHYL 2-[2-(6-CHLOROPYRIMIDIN-4-YLOXY)PHENYL]-3-METHOXYACRYLATE CHONGQING UNISPLENDOUR CHEM CO (CN) 2015-08-12 — — EP disclosed
EP-2537832-B1 METHOD FOR PREPARING (E)-METHYL 2-[2-(6-CHLOROPYRIMIDIN-4-YLOXY)PHENYL]-3-METHOXYACRYLATE CHONGQING UNISPLENDOUR CHEM CO (CN) 2015-08-12 — — EP disclosed
EP-2076498-B1 PREPARATION OF AZOXYSTROBIN SYNGENTA LTD (GB) 2015-02-25 — — EP disclosed
EP-2537832-A4 METHOD FOR PREPARING (E)-METHYL 2-[2-(6-CHLOROPYRIMIDIN-4-YLOXY)PHENYL]-3-METHOXYACRYLATE CHONGQING UNISPLENDOUR CHEM CO (CN) 2014-08-06 — — EP disclosed
EP-2537832-A1 METHOD FOR PREPARING (E)-METHYL 2-[2-(6-CHLOROPYRIMIDIN-4-YLOXY)PHENYL]-3-METHOXYACRYLATE Chongqing Unisplendour Chemical Co., Ltd. (CN) 2012-12-26 — — EP disclosed
EP-2537832-A1 METHOD FOR PREPARING (E)-METHYL 2-[2-(6-CHLOROPYRIMIDIN-4-YLOXY)PHENYL]-3-METHOXYACRYLATE Chongqing Unisplendour Chemical Co., Ltd. (CN) 2012-12-26 — — EP disclosed
WO-2012037764-A1 METHOD FOR PREPARING (E)-METHYL 2-[2-(6-CHLOROPYRIMIDIN-4-YLOXY)PHENYL]-3-METHOXYACRYLATE 重庆紫光化工股份有限公司 (CN) 2012-03-29 — — WO disclosed
WO-2012037764-A1 METHOD FOR PREPARING (E)-METHYL 2-[2-(6-CHLOROPYRIMIDIN-4-YLOXY)PHENYL]-3-METHOXYACRYLATE 重庆紫光化工股份有限公司 (CN) 2012-03-29 — — WO disclosed