Sugi Predict

Sugi Predict / Compounds / SCHEMBL713693

SCHEMBL713693

SCHEMBL713693

C/C=C(/C(=O)O)c1ccccc1Oc1cc(Cl)ncn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ NPSR1 Q6W5P4 3/20 0.36
▸ HTT P42858 3/20 0.35
▸ MAPT P10636 3/20 0.35
▸ LMNA P02545 2/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ RORC P51449 1/20 0.35
▸ RORB Q92753 1/20 0.35
▸ HSP90AA1 P07900 1/20 0.35
▸ XBP1 P17861 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ KMO O15229 1/20 0.35
▸ CYP1A2 P05177 2/20 0.35
▸ CYP2C9 P11712 2/20 0.35
▸ CYP2C19 P33261 2/20 0.35
▸ ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5132454 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL6563664 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL29391212 0.89 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL713694 0.89 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL713692 0.89 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL4740524 0.89 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL12503892 0.88 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL15298018 0.88 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL2854208 0.87 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1
SCHEMBL2857206 0.86 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof UPL LTD (IN) 2024-07-02 — — US claimed
EP-4317137-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF Anhui Guangxin Agrochemical Co., Ltd. (CN) 2024-02-07 — — EP claimed
WO-2023226456-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF 安徽广信农化股份有限公司 2023-11-30 — — WO claimed
WO-2023203574-A1 A PROCESS FOR PREPARATION OF AZOXYSTROBIN NACL INDUSTRIES LIMITED (IN) 2023-10-26 — — WO claimed
EP-3660005-B1 METHOD FOR PREPARING AZOXYSTROBIN SINON CORP (TW) 2022-06-29 — — EP claimed
US-20220185784-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF UPL LTD (IN) 2022-06-16 — — US claimed
EP-3956317-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF UPL Limited (IN) 2022-02-23 — — EP claimed
WO-2020212919-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF UPL LIMITED (IN) 2020-10-22 — — WO claimed
EP-3660005-A1 METHOD FOR PREPARING AZOXYSTROBIN Sinon Corporation (TW) 2020-06-03 — — EP claimed
US-20200165210-A1 METHOD FOR PREPARING AZOXYSTROBIN SINON CORPORATION (TW) 2020-05-28 — — US claimed
US-7084272-B2 Process for the preparation of azoxystrobin and analogues thereof SYNGENTA LIMITED (GB) 2006-08-01 — — US claimed
US-20040242607-A1 Process for the preparation of azoxystrobin and analogues thereof SYNGENTA LIMITED (GB) 2004-12-02 — — US claimed
EP-1399427-B1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN AND ANALOGUES THEREOF SYNGENTA LTD (GB) 2004-11-03 — — EP claimed
CN-114957134-B Method for preparing azoxystrobin and intermediate thereof 安徽广信农化股份有限公司 2024-07-16 — — CN disclosed
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof UPL LTD (IN) 2024-07-02 — — US disclosed
CN-118084805-A Method for preparing azoxystrobin and intermediate thereof 安徽广信农化股份有限公司 2024-05-28 — — CN disclosed
WO-2008043977-A1 PROCESS FOR PREPARING 6-PHEN0XYPYRIMIDIN-4-OL DERIVATIVES IN THE PRESENCE OF A QUINUCLIDINE OR A N-METHYL PYRROLIDINE DERIVATIVE SYNGENTA LIMITED (GB) 2008-04-17 — — WO disclosed
WO-2008043978-A1 PREPARATION OF AZOXYSTROBIN SYNGENTA LIMITED (GB) 2008-04-17 — — WO disclosed
EP-1891020-A2 PROCESSES FOR THE PREPARATION OF AZOXYSTROBIN USING DABCO AS A CATALYST AND NOVEL INTERMEDIATES USED IN THE PROCESSES Syngenta Limited (GB) 2008-02-27 — — EP disclosed
WO-2006114572-A2 PROCESSES FOR THE PREPARATION OF AZOXYSTROBIN USING DABCO AS A CATALYST AND NOVEL INTERMEDIATES USED IN THE PROCESSES SYNGENTA LIMITED (GB) 2006-11-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242607-A1 Process for the preparation of azoxystrobin and analogues thereof CYP4F2, PAH, FBL SMN1; SMN2 4537/4885ALDH1A1 650/4885MEN1 1175/4885
US-20200165210-A1 METHOD FOR PREPARING AZOXYSTROBIN CA4, MLN, CA2 SMN1; SMN2 4457/4885ALDH1A1 2250/4885MEN1 257/4885
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof NISCH, STS, SNX2 SMN1; SMN2 3076/4885ALDH1A1 1069/4885MEN1 914/4885
US-20220185784-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF NISCH, STS, SNX2 SMN1; SMN2 3076/4885ALDH1A1 1069/4885MEN1 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.