Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560933 | 0.97 | MAPT (0.52) | MAPTSMN1; SMN2RARBTHRBTSHR | |
| SCHEMBL6562379 | 0.93 | MAPT (0.52) | MAPTSMN1; SMN2RARBTHRBTSHR | |
| SCHEMBL6564025 | 0.93 | MAPT (0.52) | MAPTSMN1; SMN2RARBTHRBTSHR | |
| SCHEMBL6561998 | 0.90 | TP53 (0.46) | MAPTSMN1; SMN2THRBTSHRALDH1A1 | |
| SCHEMBL6547272 | 0.89 | PDCD1 (0.44) | MAPTSMN1; SMN2THRBTSHRALDH1A1 | |
| SCHEMBL6390324 | 0.88 | TSHR (0.45) | MAPTSMN1; SMN2RARBTHRBTSHR | |
| SCHEMBL6388175 | 0.88 | TSHR (0.45) | MAPTSMN1; SMN2RARBTHRBTSHR | |
| SCHEMBL6562073 | 0.86 | CYP4F2 (0.48) | MAPTSMN1; SMN2RARBTHRBTSHR | |
| SCHEMBL6549016 | 0.86 | MAPT (0.47) | MAPTTSHRALDH1A1KMT2APRSS1 | |
| SCHEMBL6561968 | 0.85 | PRSS1 (0.44) | MAPTSMN1; SMN2THRBTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225212-B1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6677475-B2 | FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20020146517-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. | 2002-10-10 | — | — | US | disclosed |
| EP-1225212-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-07-24 | — | — | EP | disclosed |