Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562379 | 1.00 | MAPT (0.52) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL6563854 | 0.93 | MAPT (0.47) | MAPTTHRBSMN1; SMN2KMT2ACYP4F2 | |
| SCHEMBL6562073 | 0.93 | CYP4F2 (0.48) | MAPTTHRBSMN1; SMN2KMT2AACACB | |
| SCHEMBL6560933 | 0.92 | MAPT (0.52) | MAPTTHRBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL6561998 | 0.92 | TP53 (0.46) | MAPTTHRBSMN1; SMN2KMT2ACYP4F2 | |
| SCHEMBL6547272 | 0.92 | PDCD1 (0.44) | MAPTTHRBSMN1; SMN2KMT2ATP53 | |
| SCHEMBL6549016 | 0.88 | MAPT (0.47) | MAPTKMT2ATSHRNPC1ALDH1A1 | |
| SCHEMBL6561968 | 0.87 | PRSS1 (0.44) | MAPTTHRBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL6562349 | 0.87 | MAPT (0.42) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL6563522 | 0.86 | MAPT (0.51) | MAPTTHRBSMN1; SMN2KMT2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225212-B1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6677475-B2 | FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-01-13 | — | — | US | disclosed |
| EP-1225212-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-07-24 | — | — | EP | disclosed |