SCHEMBL6563870

SCHEMBL6563870

CCCC(=O)Oc1ccc(C(=O)Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.57
CTNNB1 P35222 1/20 0.57
KMT2A Q03164 11/20 0.52
ALDH1A1 P00352 3/20 0.52
MAPT P10636 2/20 0.52
LMNA P02545 1/20 0.52
HTT P42858 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ESR1 P03372 5/20 0.51
HIF1A Q16665 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
RECQL P46063 1/20 0.51
ELANE P08246 2/20 0.47
RAB9A P51151 1/20 0.47
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
STS P08842 1/20 0.41
MEN1 O00255 1/20 0.41
SLC22A2 O15244 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11115353 0.88 KMT2A (0.55) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL11233043 0.87 KMT2A (0.57) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL9816516 0.87 KMT2A (0.57) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL10349269 0.87 KMT2A (0.57) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL8081633 0.87 KMT2A (0.57) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL8861904 0.87 KMT2A (0.57) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL11023644 0.87 BCL9 (0.70) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL968516 0.85 KMT2A (0.70) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL11375092 0.84 KMT2A (0.64) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL6562062 0.84 BCL9 (0.58) BCL9CTNNB1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1225212-B1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL CO (JP) 2004-03-24 EP disclosed
US-6677475-B2 FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2004-01-13 US disclosed
US-20020146517-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. 2002-10-10 US disclosed
EP-1225212-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-07-24 EP disclosed