SCHEMBL6563905

SCHEMBL6563905

O=c1oc(-c2ccc(-c3nc4ccc([N+](=O)[O-])cc4c(=O)o3)cc2)nc2ccc([N+](=O)[O-])cc12

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.78
MEN1 O00255 5/20 0.78
KMT2A Q03164 5/20 0.78
MAPT P10636 5/20 0.78
TDP1 Q9NUW8 1/20 0.78
L3MBTL1 Q9Y468 2/20 0.72
APEX1 P27695 1/20 0.65
ELANE P08246 2/20 0.64
NPC1 O15118 5/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
ALDH1A1 P00352 2/20 0.62
MMP2 P08253 3/20 0.56
MMP9 P14780 3/20 0.56
MMP8 P22894 3/20 0.56
MMP13 P45452 3/20 0.56
MCL1 Q07820 1/20 0.56
ATM Q13315 1/20 0.56
F7 P08709 1/20 0.54
F3 P13726 1/20 0.54
C1R P00736 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565102 0.93 RAB9A (0.69) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL6169453 0.90 RAB9A (0.65) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL913329 0.88 APEX1 (0.66) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL6567235 0.88 MEN1 (0.72) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL913677 0.88 MEN1 (0.73) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL12758424 0.87 RAB9A (0.62) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL11812017 0.85 MAPT (0.76) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL12758430 0.85 APEX1 (0.61) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL692792 0.84 MEN1 (1.00) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL29576857 0.84 MEN1 (1.00) RAB9AMEN1KMT2AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed