SCHEMBL6567235

SCHEMBL6567235

O=c1oc(-c2ccc(-c3nc4cc([N+](=O)[O-])ccc4c(=O)o3)cc2)nc2cc([N+](=O)[O-])ccc12

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.72
KMT2A Q03164 6/20 0.72
MAPT P10636 6/20 0.72
L3MBTL1 Q9Y468 2/20 0.72
RAB9A P51151 8/20 0.70
TDP1 Q9NUW8 1/20 0.70
F7 P08709 1/20 0.68
F3 P13726 1/20 0.68
C1R P00736 3/20 0.67
ELANE P08246 2/20 0.64
NPC1 O15118 6/20 0.59
MCL1 Q07820 1/20 0.59
ATM Q13315 1/20 0.59
SMN1; SMN2 Q16637 3/20 0.58
ALDH1A1 P00352 2/20 0.55
MMP2 P08253 3/20 0.54
MMP9 P14780 3/20 0.54
MMP8 P22894 3/20 0.54
MMP13 P45452 3/20 0.54
APEX1 P27695 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31742426 0.95 RAB9A (0.75) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL31742425 0.93 MEN1 (0.64) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL11812017 0.93 MAPT (0.76) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL6170277 0.90 MEN1 (0.60) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL157666 0.89 MEN1 (0.81) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL31742429 0.88 MAPT (0.65) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL6563905 0.88 RAB9A (0.78) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL914201 0.88 MEN1 (0.68) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL31742428 0.85 F7 (0.71) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL31742427 0.85 MEN1 (0.67) MEN1KMT2AMAPTL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304538-B2 Method of producing benzoxazinone-based compound FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8304538-B2 Method of producing benzoxazinone-based compound FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20110015314-A1 ULTRAVIOLET ABSORBENT AND PRODUCTION METHOD OF THE SAME FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20110015314-A1 ULTRAVIOLET ABSORBENT AND PRODUCTION METHOD OF THE SAME FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20100256362-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND FUJIFILM CORPORATION (JP) 2010-10-07 US disclosed
US-20100256362-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND FUJIFILM CORPORATION (JP) 2010-10-07 US disclosed
WO-2009041715-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND FUJIFILM CORPORATION (JP) 2009-04-02 WO disclosed
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015314-A1 ULTRAVIOLET ABSORBENT AND PRODUCTION METHOD OF THE SAME SLC40A1, F2, SLC19A1 MEN1 108/4885KMT2A 3141/4885MAPT 1332/4885
US-20100256362-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND SDHA, CYP4X1, SDHB MEN1 1056/4885KMT2A 1631/4885MAPT 4338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.