Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 10/20 | 0.32 |
| ▸ | F10 | P00742 | 6/20 | 0.32 |
| ▸ | F7 | P08709 | 5/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563243 | 0.94 | ITGB3 (0.39) | ITGB3ITGA2BNQO2F2F10 | |
| SCHEMBL6561987 | 0.90 | ITGB3 (0.36) | ITGB3ITGA2BF2F7 | |
| SCHEMBL6565311 | 0.87 | ITGB3 (0.37) | ITGB3ITGA2BNQO2F2F10 | |
| SCHEMBL6565342 | 0.84 | ITGB3 (0.38) | ITGB3ITGA2BF2F10F7 | |
| SCHEMBL6563515 | 0.82 | F2 (0.36) | ITGB3ITGA2BF2F10F7 | |
| SCHEMBL6563523 | 0.81 | ITGB3 (0.37) | ITGB3ITGA2BNQO2F2F10 | |
| SCHEMBL6563705 | 0.78 | PRSS1 (0.35) | ITGB3ITGA2BNQO2F2F10 | |
| SCHEMBL6563285 | 0.77 | ITGB3 (0.39) | ITGB3ITGA2BNQO2F2F10 | |
| SCHEMBL6565300 | 0.77 | ITGB3 (0.36) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7670888 | 0.76 | F2 (0.38) | ITGB3ITGA2BF2F10F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |