Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 11/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565342 | 0.92 | ITGB3 (0.38) | ITGB3ITGA2BF2 | |
| SCHEMBL6565311 | 0.90 | ITGB3 (0.37) | ITGB3ITGA2BF2ALDH1A1PRSS1 | |
| SCHEMBL6561987 | 0.86 | ITGB3 (0.36) | ITGB3ITGA2BF2 | |
| SCHEMBL6563243 | 0.82 | ITGB3 (0.39) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7674133 | 0.81 | ITGB3 (0.36) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7674138 | 0.80 | PLAU (0.34) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL6565268 | 0.79 | F2 (0.38) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL6563947 | 0.77 | ITGB3 (0.37) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL6565394 | 0.76 | F2 (0.36) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL4250003 | 0.75 | ITGB3 (0.37) | ITGB3ITGA2BF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |