Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563996 | 1.00 | VDR (0.44) | VDRCYP4F2CYP4A11ACHEMAOB | |
| SCHEMBL6563985 | 1.00 | VDR (0.44) | VDRCYP4F2CYP4A11ACHEMAOB | |
| SCHEMBL6566386 | 0.89 | VDR (0.39) | VDRCYP4F2CYP4A11ACHEMAOB | |
| SCHEMBL6566376 | 0.89 | VDR (0.39) | VDRCYP4F2CYP4A11ACHEMAOB | |
| SCHEMBL6566371 | 0.89 | VDR (0.39) | VDRCYP4F2CYP4A11ACHEMAOB | |
| SCHEMBL2783371 | 0.86 | VDR (0.57) | VDR | |
| SCHEMBL2783367 | 0.86 | VDR (0.57) | VDR | |
| SCHEMBL2783364 | 0.86 | VDR (0.57) | VDR | |
| SCHEMBL6563990 | 0.83 | MRGPRX4 (0.32) | CYP4F2CYP4A11 | |
| SCHEMBL6562882 | 0.83 | CYP4F2 (0.34) | CYP4F2CYP4A11MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |