Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566382 | 0.89 | MRGPRX4 (0.32) | MRGPRX4CYP4F2CYP4A11NPC1LMNA | |
| SCHEMBL2783369 | 0.86 | MRGPRX4 (0.44) | MRGPRX4NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6563985 | 0.83 | VDR (0.44) | CYP4F2CYP4A11 | |
| SCHEMBL6563996 | 0.83 | VDR (0.44) | CYP4F2CYP4A11 | |
| SCHEMBL6563980 | 0.83 | VDR (0.44) | CYP4F2CYP4A11 | |
| SCHEMBL6562882 | 0.82 | CYP4F2 (0.34) | MRGPRX4CYP4F2CYP4A11LMNARAB9A | |
| SCHEMBL6562874 | 0.82 | CYP4F2 (0.34) | MRGPRX4CYP4F2CYP4A11LMNARAB9A | |
| SCHEMBL6566528 | 0.81 | FFAR1 (0.31) | — | |
| SCHEMBL6886939 | 0.81 | NPC1 (0.35) | MRGPRX4CYP4F2CYP4A11NPC1HPGD | |
| SCHEMBL6886943 | 0.81 | NPC1 (0.35) | MRGPRX4CYP4F2CYP4A11NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |