Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | PYGM | P11217 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563982 | 1.00 | DAO (0.33) | DAOALDH1A1POLBNPC1APEX1 | |
| SCHEMBL6885428 | 0.89 | ALOX5AP (0.33) | NPC1RAB9ATDP1MAOB | |
| SCHEMBL6885431 | 0.89 | ALOX5AP (0.33) | NPC1RAB9ATDP1MAOB | |
| SCHEMBL6566263 | 0.86 | DAO (0.30) | DAO | |
| SCHEMBL6566259 | 0.86 | DAO (0.30) | DAO | |
| SCHEMBL6562969 | 0.83 | MRGPRX4 (0.34) | ALDH1A1POLBNPC1APEX1RAB9A | |
| SCHEMBL6562973 | 0.83 | MRGPRX4 (0.34) | ALDH1A1POLBNPC1APEX1RAB9A | |
| SCHEMBL6562992 | 0.83 | MAOB (0.35) | ALDH1A1L3MBTL1MAOB | |
| SCHEMBL6562982 | 0.83 | MAOB (0.35) | ALDH1A1L3MBTL1MAOB | |
| SCHEMBL6562780 | 0.82 | VDR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |