Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562969 | 1.00 | MRGPRX4 (0.34) | MRGPRX4ALDH1A1POLBNPC1APEX1 | |
| SCHEMBL6889766 | 0.89 | MRGPRX4 (0.37) | MRGPRX4POLBNPC1RAB9ATDP1 | |
| SCHEMBL6889768 | 0.89 | MRGPRX4 (0.37) | MRGPRX4POLBNPC1RAB9ATDP1 | |
| SCHEMBL6562808 | 0.85 | MRGPRX4 (0.31) | MRGPRX4ALDH1A1PRSS1TMPRSS15 | |
| SCHEMBL6562805 | 0.85 | MRGPRX4 (0.31) | MRGPRX4ALDH1A1PRSS1TMPRSS15 | |
| SCHEMBL6562982 | 0.83 | MAOB (0.35) | MRGPRX4ALDH1A1L3MBTL1MAOB | |
| SCHEMBL6563986 | 0.83 | DAO (0.33) | ALDH1A1POLBNPC1APEX1RAB9A | |
| SCHEMBL6563982 | 0.83 | DAO (0.33) | ALDH1A1POLBNPC1APEX1RAB9A | |
| SCHEMBL6562992 | 0.83 | MAOB (0.35) | MRGPRX4ALDH1A1L3MBTL1MAOB | |
| SCHEMBL6564840 | 0.82 | VDR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |