⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865217 | 0.76 | ALDH1A1 (0.37) | — | |
| SCHEMBL6745199 | 0.74 | — | — | |
| SCHEMBL5275675 | 0.72 | MAPT (0.31) | — | |
| SCHEMBL8630779 | 0.72 | — | — | |
| SCHEMBL9865354 | 0.71 | — | — | |
| SCHEMBL6565787 | 0.69 | — | — | |
| SCHEMBL13884144 | 0.68 | TSHR (0.41) | — | |
| SCHEMBL11470209 | 0.66 | — | — | |
| Acetic Acid SCHEMBL11462194 | 0.65 | ALDH1A1 (0.32) | — | |
| SCHEMBL8628094 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110684038-B | Pharmaceutical preparation of compound of trissofene ceftriaxone sodium and new indication for treating pelvic inflammation | 广东金城金素制药有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-110396101-B | New indication of pharmaceutical preparation of troxofen ceftriaxone sodium for treating bacterial endometritis | 广东金城金素制药有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-110393720-B9 | Pharmaceutical preparation of compound of trisufen ceftriaxone sodium and new indication for treating infection of patients with low immune function | 广东金城金素制药有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-108310933-B | Preparation method of VOC remover in leather finishing workshop | 烟台大学 | 2020-10-02 | — | — | CN | claimed |
| CN-110393720-B | New indication of pharmaceutical preparation of troxofen ceftriaxone sodium for treating infection of patients with low immune function | 广东金城金素制药有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-111395017-A | Environment-friendly chlorine-bleaching-resistant and sunlight-resistant invisible printing paste and preparation method thereof | 广州明诺新材料科技有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-111379176-A | Environment-friendly sunlight-resistant printing overprinting white paste and preparation method thereof | 广州明诺新材料科技有限公司 | 2020-07-07 | — | — | CN | claimed |
| CN-110684038-A | New indication of pharmaceutical preparation of troxofen ceftriaxone sodium for treating pelvic inflammation | 广东金城金素制药有限公司 | 2020-01-14 | — | — | CN | claimed |
| US-20040002601-A1 | Method for producing cephalosporins | ACS DOBFAR S.P.A. (IT) | 2004-01-01 | — | — | US | claimed |
| EP-0746561-B1 | QUINOLONYLCARBOXAMIDOCEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ARANDA LAB SA DE CV (MX) | 1999-04-28 | — | — | EP | claimed |
| EP-0300546-B1 | Process for the preparation of cephem compounds and cephalosporin derivatives | GIST BROCADES NV (NL) | 1995-08-09 | — | — | EP | claimed |
| EP-0099580-B1 | NEW 1-OXA-1-DETHIA-CEPHALOSPORIN DERIVATIVES | MERCK & CO. INC. (US) | 1987-10-14 | — | — | EP | claimed |
| US-4661480-A | Formamido oxacephems | BEECHAM GROUP P.L.C. (GB) | 1987-04-28 | — | — | US | claimed |
| US-4534898-A | 1-Oxa-1-dethia-cephalosporin derivatives | MERCK & CO., INC. (US) | 1985-08-13 | — | — | US | claimed |
| EP-0027599-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | claimed |
| US-4472574-A | Process for the manufacture of a cephem carboxylic acid derivative | HOFFMAN-LA ROCHE INC. (US) | 1984-09-18 | — | — | US | claimed |
| EP-0099580-A1 | New 1-oxa-1-dethia-cephalosporin derivatives | MERCK & CO. INC. (US) | 1984-02-01 | — | — | EP | claimed |
| EP-0065748-A1 | Process for the preparation of a cephalosporin derivative | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-12-01 | — | — | EP | claimed |
| US-4332800-A | BACTERICIDES CONTAINING 7-AMINOTHIADIAZOLE GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-01 | — | — | US | claimed |
| EP-0027599-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-29 | — | — | EP | claimed |